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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Primary cutaneous amyloidosis

Introduction

Overview

Overview

Primary cutaneous amyloidosis is a form of amyloidosis associated with oncostatin M receptor.[1][2] This type of amyloidosis has been divided into the following types:[3]:520

  • Macular amyloidosis is a cutaneous condition characterized by itchy, brown, rippled macules usually located on the interscapular region of the back.[3]:521 Combined cases of lichen and macular amyloidosis are termed biphasic amyloidosis, and provide support to the theory that these two variants of amyloidosis exist on the same disease spectrum. [4]
  • Lichen amyloidosis is a cutaneous condition characterized by the appearance of occasionally itchy lichenoid papules, typically appearing bilaterally on the shins.[3]:521
  • Nodular amyloidosis is a rare cutaneous condition characterized by nodules that involve the acral areas.[3]:521
Diagnosis

Diagnosis

Physical Examination

Skin

Macular Amyloidosis
Lower Extremity
Trunk
Nodular Amyloidosis
Face
Lichen Amyloidosus
Extremity
Trunk

See also

References

  1. ↑ “Amyloid”.
  2. ↑ Arita K, South AP, Hans-Filho G; et al. (January 2008). “Oncostatin M receptor-beta mutations underlie familial primary localized cutaneous amyloidosis”. Am. J. Hum. Genet. 82 (1): 73–80. doi:10.1016/j.ajhg.2007.09.002. PMC 2253984. PMID 18179886.
  3. ↑ 3.0 3.1 3.2 3.3 James, William D.; Berger, Timothy G.; et al. (2006). Andrews’ Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  4. ↑ Lichen amyloidosis of the auricular concha Craig, E. (2006) Dermatology Online Journal 12 (5): 1, University of California, Davis Department of Dermatology
  5. ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 5.16 5.17 5.18 “Dermatology Atlas”.

References

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]