Primary sclerosing cholangitis other diagnostic studies
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]
Overview
Overview
A liver biopsy may be performed in patients with primary sclerosing cholangitis, although it is not necessary for diagnosis. The pathognomonic finding of periductal onion-skin fibrosis is rarely seen. However, a liver biopsy may be useful when the small ducts subtype of the primary sclerosing cholangitis or that associated with autoimmune hepatitis are suspected.
Other Diagnostic Studies
Other Diagnostic Studies
Liver Biopsy
A liver biopsy may be performed in patients with primary sclerosing cholangitis, although it is not necessary for diagnosis. The pathognomonic finding of periductal onion-skin fibrosis is rarely seen. However, a liver biopsy may be useful when the small ducts subtype of the primary sclerosing cholangitis or that associated with autoimmune hepatitis are suspected.[1][2][3]
References
References
- ↑ Lazaridis KN, LaRusso NF (2016). “Primary Sclerosing Cholangitis”. N. Engl. J. Med. 375 (12): 1161–70. doi:10.1056/NEJMra1506330. PMID 27653566.
- ↑ Eaton JE, Talwalkar JA, Lazaridis KN, Gores GJ, Lindor KD (2013). “Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management”. Gastroenterology. 145 (3): 521–36. doi:10.1053/j.gastro.2013.06.052. PMC 3815445. PMID 23827861.
- ↑ Lazaridis KN, LaRusso NF (2015). “The Cholangiopathies”. Mayo Clin. Proc. 90 (6): 791–800. doi:10.1016/j.mayocp.2015.03.017. PMC 4533104. PMID 25957621.
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