Primary sclerosing cholangitis surgery
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]
Overview
Overview
Primary sclerosing cholangitis is a progressive disease that ultimately leads to end-stage liver disease (ESLD). Endoscopic management can be targeted for dominant strictures or as palliative treatment. However, current gold standard of treatment for primary sclerosing cholangitis is liver transplantation. Despite liver transplantation, disease may still recur in 25% of patients.
Surgery
Surgery
- Primary sclerosing cholangitis is a progressive disease that ultimately leads to end stage liver disease (ESLD).
- Endoscopic management can be targeted for dominant strictures or as palliative treatment; however, current gold standard of treatment for primary sclerosing cholangitis is liver transplantation.
- Despite liver transplantation, disease may still recur in 25% of patients.[1][2][3]
References
References
- ↑ Lazaridis KN, LaRusso NF (2016). “Primary Sclerosing Cholangitis”. N. Engl. J. Med. 375 (12): 1161–70. doi:10.1056/NEJMra1506330. PMID 27653566.
- ↑ Tischendorf JJ, Hecker H, Krüger M, Manns MP, Meier PN (2007). “Characterization, outcome, and prognosis in 273 patients with primary sclerosing cholangitis: A single center study”. Am. J. Gastroenterol. 102 (1): 107–14. doi:10.1111/j.1572-0241.2006.00872.x. PMID 17037993.
- ↑ Fosby B, Karlsen TH, Melum E (2012). “Recurrence and rejection in liver transplantation for primary sclerosing cholangitis”. World J. Gastroenterol. 18 (1): 1–15. doi:10.3748/wjg.v18.i1.1. PMC 3251800. PMID 22228965.
Looking for the patient version?
© 2026 MyEClinic – IFTM Institut für Telematik in der Medizin GmbH