Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Primary sclerosing cholangitis surgery
Introduction
Overview
Overview
Primary sclerosing cholangitis is a progressive disease that ultimately leads to end-stage liver disease (ESLD). Endoscopic management can be targeted for dominant strictures or as palliative treatment. However, current gold standard of treatment for primary sclerosing cholangitis is liver transplantation. Despite liver transplantation, disease may still recur in 25% of patients.
Surgery
Surgery
- Primary sclerosing cholangitis is a progressive disease that ultimately leads to end stage liver disease (ESLD).
- Endoscopic management can be targeted for dominant strictures or as palliative treatment; however, current gold standard of treatment for primary sclerosing cholangitis is liver transplantation.
- Despite liver transplantation, disease may still recur in 25% of patients.[1][2][3]
References
References
- ↑ Lazaridis KN, LaRusso NF (2016). “Primary Sclerosing Cholangitis”. N. Engl. J. Med. 375 (12): 1161–70. doi:10.1056/NEJMra1506330. PMID 27653566.
- ↑ Tischendorf JJ, Hecker H, Krüger M, Manns MP, Meier PN (2007). “Characterization, outcome, and prognosis in 273 patients with primary sclerosing cholangitis: A single center study”. Am. J. Gastroenterol. 102 (1): 107–14. doi:10.1111/j.1572-0241.2006.00872.x. PMID 17037993.
- ↑ Fosby B, Karlsen TH, Melum E (2012). “Recurrence and rejection in liver transplantation for primary sclerosing cholangitis”. World J. Gastroenterol. 18 (1): 1–15. doi:10.3748/wjg.v18.i1.1. PMC 3251800. PMID 22228965.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]