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ProMACE-MOPP regimen

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Overview

Overview

ProMACE-MOPP regimen refers to a regimen consisting of prolix (prednisone), methotrexate, adriamycin (doxorubicin), cyclophosphamide, etoposide, mustargen (mechlorethamine), oncovin (vincristine), procarbazine, prednisone used to treat diffuse large B-cell lymphoma[1] and primary CNS lymphoma.[2]

Regimen

Regimen

ProPrednisone

MMethotrexate

AAdriamycin (Doxorubicin)

CCyclophosphamide

EEtoposide

MMustargen (Mechlorethamine)

OOncovin (Vincristine)

PProcarbazine

PPrednisone

Indications

Indications

References

References

  1. 1.0 1.1 Sertoli MR, Santini G, Chisesi T, Congiu AM, Rubagotti A, Contu A; et al. (1994). “MACOP-B versus ProMACE-MOPP in the treatment of advanced diffuse non-Hodgkin’s lymphoma: results of a prospective randomized trial by the non-Hodgkin’s Lymphoma Cooperative Study Group”. J Clin Oncol. 12 (7): 1366–74. PMID 7517442.
  2. 2.0 2.1 Yamanaka R, Morii K, Shinbo Y, Takeuchi S, Tamura T, Hondoh H; et al. (2005). “Modified ProMACE-MOPP hybrid regimen with moderate-dose methotrexate for patients with primary CNS lymphoma”. Ann Hematol. 84 (7): 447–55. doi:10.1007/s00277-005-1005-9. PMID 15747120.

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