Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Progeria epidemiology and demographics
Introduction
Overview
Overview
Hutchinson-Gilford progeria syndrome (HGPS) is an extremely rare hereditary disease. The incidence of Hutchinson-Gilford progeria syndrome (HGPS) is very rare. The usual age of diagnosis for Hutchinson-Gilford progeria syndrome (HGPS) ia around two to three years of age. Approximately 100 cases of Hutchinson-Gilford progeria syndrome (HGPS) have been reported in the literature till now worldwide.
Epidemiology and Demographics
Epidemiology and Demographics
Incidence
- The incidence of Hutchinson-Gilford progeria syndrome (HGPS) is approximately one in four to eight million births worldwide.[1][2]
- The incidence of Hutchinson-Gilford progeria syndrome (HGPS) in Netherlands is 1:4,000,000.[3]
Prevalence
- The prevalence of Hutchinson-Gilford progeria syndrome (HGPS) is approximately 1 in 20 million individuals worldwide.
Age
- Hutchinson-Gilford progeria syndrome (HGPS) commonly affects individuals of very younger age rather than older age.
- The median age at diagnosis is 2.9 years overall.[4]
Race
- Hutchinson-Gilford progeria syndrome (HGPS) usually affects individuals of the white race.
Gender
- Hutchinson-Gilford progeria syndrome (HGPS) affects men and women equally but males are little more commonly affected by Hutchinson-Gilford progeria syndrome than females.
- The male to female ratio is approximately 1.5:1.[5]
References
References
- ↑ Hennekam RC (2006). “Hutchinson-Gilford progeria syndrome: review of the phenotype”. Am J Med Genet A. 140 (23): 2603–24. doi:10.1002/ajmg.a.31346. PMID 16838330.
- ↑ Doubaj Y, Lamzouri A, Elalaoui SC, Laarabi FZ, Sefiani A (2011). “[Three cases of Hutchinson-Gilford progeria syndrome]”. Arch Pediatr. 18 (2): 156–9. doi:10.1016/j.arcped.2010.11.014. PMID 21251803.
- ↑ Hennekam RC (2006). “Hutchinson-Gilford progeria syndrome: review of the phenotype”. Am J Med Genet A. 140 (23): 2603–24. doi:10.1002/ajmg.a.31346. PMID 16838330.
- ↑ Hennekam RC (2006). “Hutchinson-Gilford progeria syndrome: review of the phenotype”. Am J Med Genet A. 140 (23): 2603–24. doi:10.1002/ajmg.a.31346. PMID 16838330.
- ↑ Hennekam RC (2006). “Hutchinson-Gilford progeria syndrome: review of the phenotype”. Am J Med Genet A. 140 (23): 2603–24. doi:10.1002/ajmg.a.31346. PMID 16838330.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]