Progeria risk factors
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
Overview
The most potent risk factor in the development of Hutchinson-Gilford progeria syndrome is mutation in LMNA gene.
Risk Factors
Risk Factors
- The most potent risk factor in the development of Hutchinson-Gilford progeria syndrome is mutation in LMNA gene.[1][2][3][4]
- Other than genetic there are no other risk factors mentioned
References
References
- ↑ Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L; et al. (2003). “Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome”. Nature. 423 (6937): 293–8. doi:10.1038/nature01629. PMID 12714972.
- ↑ Pollex RL, Hegele RA (2004). “Hutchinson-Gilford progeria syndrome”. Clin Genet. 66 (5): 375–81. doi:10.1111/j.1399-0004.2004.00315.x. PMID 15479179.
- ↑ Cao H, Hegele RA (2003). “LMNA is mutated in Hutchinson-Gilford progeria (MIM 176670) but not in Wiedemann-Rautenstrauch progeroid syndrome (MIM 264090)”. J Hum Genet. 48 (5): 271–4. doi:10.1007/s10038-003-0025-3. PMID 12768443.
- ↑ Mazereeuw-Hautier J, Wilson LC, Mohammed S, Smallwood D, Shackleton S, Atherton DJ; et al. (2007). “Hutchinson-Gilford progeria syndrome: clinical findings in three patients carrying the G608G mutation in LMNA and review of the literature”. Br J Dermatol. 156 (6): 1308–14. doi:10.1111/j.1365-2133.2007.07897.x. PMID 17459035.
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