Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Psoriasis laboratory findings
Introduction
Overview
Overview
Laboratory findings consistent with the diagnosis of psoriasis include increased levels of Long Pentraxin 3 protein (PTX3) and elevated complement levels.
Laboratory Findings
Laboratory Findings
Enzyme linked immunosorbent assay (ELISA)
- In patients with severe psoriasis, increased levels of Long Pentraxin 3 protein (PTX3) can be observed in plasma and in monocytic cultures by enzyme linked immunosorbent assay (ELISA).[1]
Serum complement levels
The following abnormalities of serum complement levels may be observed in cases of psoriasis:[2]
- Increased serum IgA
- Increased C3 in phalyngeal arthropathy associated with psoriasis
- Increased C4
- Increased C3PA concentrations
- Increased CRP concentration in sacroiliitis associated with psoriasis
References
References
- ↑ Bevelacqua V, Libra M, Mazzarino MC, Gangemi P, Nicotra G, Curatolo S, Massimino D, Plumari A, Merito P, Valente G, Stivala F, La Greca S, Malaponte G (2006). “Long pentraxin 3: a marker of inflammation in untreated psoriatic patients”. Int. J. Mol. Med. 18 (3): 415–23. PMID 16865225.
- ↑ Vinje O, Møller P, Mellbye OJ (1980). “Laboratory findings in patients with psoriasis, with special reference to immunological parameters, associations with arthropathy and sacro-iliitis”. Scand. J. Rheumatol. 9 (2): 97–105. PMID 6159678.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]