Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Pulmonary hypertension historical perspective
Introduction
Overview
Overview
Pulmonary hypertension was first described by Ernst von Romberg, a German physician, in 1891.
Historical Perspective
Historical Perspective
- Pulmonary hypertension was first described by Ernst von Romberg, a German physician, in 1891.
- In 1929, Werner Forssman demonstrated that it was possible to perform right-sided catheterization in humans by performing catheterization on himself.
- In 1951, Dresdale coined the term primary pulmonary hypertension after describing series of cases of this new pathology. He also investigated the effects of tolzoline in a woman with pulmonary arterial hypertension causing a sudden reduction in pulmonary vascular resistance.
- In the late 1960s, there was an epidemic of pulmonary arterial hypertension induced by aminorex, which sparked interest in the disease.
- Pulmonary hypertension was first classified into primary and secondary in 1973 during the World Health Organization (WHO) meeting on PH in Geneva, Switzerland.
- Bosentan was approved to treat pulmonary hypertension in 2001, and sildenafil was approved in 2005.[1]
References
References
- ↑ Barst RJ (2008). “Pulmonary hypertension: past, present and future”. Ann Thorac Med. 3 (1): 1–4. doi:10.4103/1817-1737.37832. PMC 2700428. PMID 19561874.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]: Associate Editor(s)-in-Chief: José Eduardo Riceto Loyola Junior, M.D.[2]