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Pyrovalerone

Overview

Overview

Pyrovalerone (Centroton, Thymergix) is a stimulant drug developed in the late 1960s and used in France and some other European countries. This drug is now rarely prescribed due to problems with abuse and dependence [1] , but is still rarely prescribed either as an appetite suppresant or for treating chronic fatigue and lethargy. [2] Side effects of pyrovalerone include loss of appetite, anxiety, insomnia and tremor. Withdrawal syndrome following abuse causes depression. [3] Pyrovalerone is a Schedule V drug in the USA. It is closely related to some other stimulant drugs such as prolintane and MDPV


CAS# 1147-62-2 (pyrovalerone hydrochloride); 3563-49-3 (pyrovalerone freebase)

References

References

  1. Deniker P, Loo H, Cuche H, Roux JM. Abuse of pyrovalerone by drug addicts. Annales Medico-Psychologiques (Paris) 1975 Nov;2(4):745-8.
  2. Gardos G, Cole JO. Evaluation of pyrovalerone in chronically fatigued volunteers. Current Therapeutic Research, Clinical and Experimental. 1971 Oct;13(10):631-5.
  3. http://www.biam2.org/www/Etr8623.html

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