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RAP1GDS1 gene

Introduction

Rap1 GTPase-GDP dissociation stimulator 1 is an enzyme that in humans is encoded by the RAP1GDS1 gene.[1][2][3]

Interactions

Interactions

RAP1GDS1 has been shown to interact with KIFAP3,[4] HRAS[5] and RHOA.[5]

References

References

  1. ↑ Riess O, Epplen C, Siedlaczck I, Epplen JT (Jan 1994). “Chromosomal assignment of the human smg GDP dissociation stimulator gene to human chromosome 4q21-q25”. Hum Genet. 92 (6): 629–30. doi:10.1007/BF00420952. PMID 8262526.
  2. ↑ Tew GW, Lorimer EL, Berg TJ, Zhi H, Li R, Williams CL (Jan 2008). “SmgGDS regulates cell proliferation, migration, and NF-kappaB transcriptional activity in non-small cell lung carcinoma”. J Biol Chem. 283 (2): 963–76. doi:10.1074/jbc.M707526200. PMID 17951244.
  3. ↑ “Entrez Gene: RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1”.
  4. ↑ Shimizu, K; Kawabe H; Minami S; Honda T; Takaishi K; Shirataki H; Takai Y (Oct 1996). “SMAP, an Smg GDS-associating protein having arm repeats and phosphorylated by Src tyrosine kinase”. J. Biol. Chem. UNITED STATES. 271 (43): 27013–7. doi:10.1074/jbc.271.43.27013. ISSN 0021-9258. PMID 8900189.
  5. ↑ 5.0 5.1 Vikis, Haris G; Stewart Scott; Guan Kun-Liang (Apr 2002). “SmgGDS displays differential binding and exchange activity towards different Ras isoforms”. Oncogene. England. 21 (15): 2425–32. doi:10.1038/sj.onc.1205306. ISSN 0950-9232. PMID 11948427.
Further reading

Further reading