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RIPOR2

RHO family interacting cell polarization regulator 2 is a protein that in humans is encoded by the RIPOR2 gene.[1]

Function

Function

The protein encoded by this gene stimulates the formation of a non-mitotic multinucleate syncytium from proliferative cytotrophoblasts during trophoblast differentiation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2013].

Clinical significance

Clinical significance

Mutations in RIPOR2 are associated to hearing loss .[2]

References

References

  1. “Entrez Gene: Family with sequence similarity 65, member B”.
  2. Diaz-Horta O, Subasioglu-Uzak A, Grati M, DeSmidt A, Foster J, Cao L, Bademci G, Tokgoz-Yilmaz S, Duman D, Cengiz FB, Abad C, Mittal R, Blanton S, Liu XZ, Farooq A, Walz K, Lu Z, Tekin M (July 2014). “FAM65B is a membrane-associated protein of hair cell stereocilia required for hearing”. Proceedings of the National Academy of Sciences of the United States of America. 111 (27): 9864–8. doi:10.1073/pnas.1401950111. PMC 4103326. PMID 24958875.
Further reading

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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