Health Dictionary Find a Doctor

Rapidly progressive glomerulonephritis historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Jogeet Singh Sekhon, M.D. [2]

Overview

Overview

In 1919 Ernst Goodpasture made case reports about glomerulnophritis and pulmonary haemorrhages. Stanton and Tait from Australia studied these case reports and then named the findings as Goodpasture syndrome in 1958. They gave the anti GBM antibodies classification and discovered RPGN in these cases. In 1960s electron microscopy and immunofluorescence helped to learn RPNG on immunological level.

Historical perspective

Historical perspective

  • Ernst Goodpasture made case reports about glomerulnophritis and pulmonary haemorrhages in 1919[1].
  • Stanton and Tait from Australia studied these case reports and then named the findings as Goodpasture syndrome in 1958.
  • They gave the anti GBM antibodies classification and discovered RPGN in these cases.
  • In 1960s, electron microscopy and immunofluorescence helped to learn RPNG on immunological level.
References

References

  1. McAdoo SP, Pusey CD (2017). “Anti-Glomerular Basement Membrane Disease”. Clin J Am Soc Nephrol. 12 (7): 1162–1172. doi:10.2215/CJN.01380217. PMC 5498345. PMID 28515156.

Looking for the patient version?

Back to the patient-friendly article

© 2026 MyEClinic – IFTM Institut für Telematik in der Medizin GmbH