Reflux nephropathy natural history, complications and prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

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Overview

Natural History

Complications

The end results of RN are

Hypertension
Proteinuria
Chronic Renal Failure
ESRD (end stage renal disease)
Blockage of the ureter after surgery
Chronic or repeat urinary tract infections
Kidney infection
Nephrotic syndrome
Persistent reflux
Scarring of the kidneys

Prognosis

The outcome varies, depending on the severity of the reflux. Some people with reflux nephropathy will not lose kidney function over time, even though their kidneys are damaged. However, kidney damage may be permanent. If only one kidney is involved, the other kidney should keep working normally.

Reflux nephropathy may cause kidney failure in both children and adults.

References

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