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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Renal agenesis epidemiology and demographics

Introduction

Overview

Overview

The general incidence of unilateral renal agenesis (URA) has been reported to be approximately 1 in 2031 individuals. Males are more commonly affected by unilateral renal agenesis (URA) than females. The incidence of bilateral renal agenesis (BRA) is approximately 1 in every 3000 pregnancies. The mortality rate of bilateral renal agenesis (BRA) without prenatal therapy is 100 %.

Epidemiology and Demographics

Epidemiology and Demographics

Incidence

  • The general incidence of unilateral renal agenesis (URA) has been reported to be approximately 1 in 2031 individuals, however, the incidence of URA based on prenatal studies alone has been reported to be 1 in 8091.[1]
  • The incidence of bilateral renal agenesis (BRA) is approximately 1 in every 3000 pregnancies.[2][3]

Prevalence

A report showed that the overall prevalence of unilateral renal agenesis (URA) was 4 per 10,000 in all births which included terminations of pregnancy (TOP) and intrauterine deaths (IUD).[4]

Mortality rate

The mortality rate of bilateral renal agenesis (BRA) without prenatal therapy is 100%.[5]

Gender

Males are more commonly affected by unilateral renal agenesis (URA) than females. It has been reported that 63% of the patients with URA are male.[1]

References

References

  1. ↑ 1.0 1.1 Westland R, Schreuder MF, Ket JC, van Wijk JA (2013). “Unilateral renal agenesis: a systematic review on associated anomalies and renal injury”. Nephrol Dial Transplant. 28 (7): 1844–55. doi:10.1093/ndt/gft012. PMID 23449343.
  2. ↑ Bienstock JL, Birsner ML, Coleman F, Hueppchen NA (2014). “Successful in utero intervention for bilateral renal agenesis”. Obstet Gynecol. 124 (2 Pt 2 Suppl 1): 413–5. doi:10.1097/AOG.0000000000000339. PMID 25004316.
  3. ↑ Isaksen CV, Eik-Nes SH, Blaas HG, Torp SH (2000). “Fetuses and infants with congenital urinary system anomalies: correlation between prenatal ultrasound and postmortem findings”. Ultrasound Obstet Gynecol. 15 (3): 177–85. doi:10.1046/j.1469-0705.2000.00065.x. PMID 10846770.
  4. ↑ Laurichesse Delmas H, Kohler M, Doray B, Lémery D, Francannet C, Quistrebert J; et al. (2017). “Congenital unilateral renal agenesis: Prevalence, prenatal diagnosis, associated anomalies. Data from two birth-defect registries”. Birth Defects Res. 109 (15): 1204–1211. doi:10.1002/bdr2.1065. PMID 28722320.
  5. ↑ Huber C, Shazly SA, Blumenfeld YJ, Jelin E, Ruano R (2019). “Update on the Prenatal Diagnosis and Outcomes of Fetal Bilateral Renal Agenesis”. Obstet Gynecol Surv. 74 (5): 298–302. doi:10.1097/OGX.0000000000000670. PMID 31098643.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]