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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Renal compensation

Introduction

Overview

Overview

Renal compensation is a mechanism by which the kidneys can regulate the plasma pH. It is slower than respiratory compensation, but has a greater ability to restore normal values.

Renal compensation in acid-base disorders

Renal compensation in acid-base disorders

See also: Compensatory responses for acid-base disorders

In respiratory acidosis, the kidney produces and excretes ammonium (NH4+) and monophosphate, generating bicarbonate in the process while clearing acid.[1]

In respiratory alkalosis, less HCO3- is reabsorbed, thus lowering the pH.[2]

References

References

  1. ↑ Essentials of Human Physiology by Thomas M. Nosek. Section 7/7ch12/7ch12p45.
  2. ↑ Essentials of Human Physiology by Thomas M. Nosek. Section 7/7ch12/7ch12p48.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]