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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Renal papillary necrosis classification

Introduction

Overview

Overview

Renal papillary necrosis may be classified according to the severity of renal parenchymal lesions into two subtypes: Medullary and Papillary.

Classification

Classification

Renal papillary necrosis may be classified according to the severity of renal parenchymal lesions into two subtypes^[1]:
- Medullary
  - focal necrotic areas, without fornices involvement
- Papillary
  - involvement of the whole calyceal systems and papillary areas

Staging of Renal papillary necrosis

Staging of Renal papillary necrosis

According to the histological finding of renal papillary necrosis, there are five grades based on the severity. “Renal Papillary Necrosis – an overview | ScienceDirect Topics”.
- Grade 1
  - involvement of microvasculature, loop of Henle, and interstitial cells, which replaced by eosinophilic material
  - intact collecting ducts
- Grade 2
  - necrosis of apex of the papilla
- Grade 3
  - necrosis that extends to mid-papilla
- Grade 4
  - necrosis that extends to base of the papilla
- Grade 5
  - necrosis that extends to the extra-medullary area

References

References

↑ Madu AJ, Okoye AE, Ajuba IC, Madu KA, Anigbo C, Agu K (2016). “Prevalence and associations of symptomatic renal papillary necrosis in sickle cell anemia patients in South-Eastern Nigeria”. Niger J Clin Pract. 19 (4): 471–4. doi:10.4103/1119-3077.183299. PMID 27251962.

Editor-In-Chief: Please help WikiDoc by adding content here. It’s easy! Click here to learn about editing.
C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nasrin Nikravangolsefid, MD-MPH [2]