Renal tubular acidosis (patient information)

Renal tubular acidosis is a condition in which there is too much acid in the body fluids.

Most symptoms are caused by the underlying disease or condition that is causing the renal tubular acidosis or inherited disorder of kidneys. Renal tubular acidosis itself usually causes rapid breathing. Confusion or lethargy may also occur. Severe acidosis can lead to shock or death. In some situations, acidosis can be a mild, chronic (ongoing) condition.

Renal tubular acidosis occurs when the body produces too much acid, or when the kidneys are not removing enough acid from the body.

• Diabetic acidosis (also called diabetic ketoacidosis and DKA) develops when substances known as ketone bodies, which are acidic, build up during uncontrolled diabetes
• Hyperchloremic acidosis results from excessive loss of sodium bicarbonate from the body, as can happen with severe diarrhea
• Lactic acidosis is a buildup of lactic acid. It can be caused by:
  • Alcohol
  • Cancer
  • Exercising for a very long time
  • Liver failure
  • Low blood sugar (hypoglycemia)
  • Medications such as salicylates
  • Prolonged lack of oxygen from shock, heart failure, or severe anemia
  • Seizures

Other causes of acidosis include:

• Poisoning by aspirin, ethylene glycol (found in antifreeze), or methanol
• Severe dehydration

Patient suffering from any of the conditions mentioned above are at risk of renal tubular acidosis.

Seek medical treatment if you develop symptoms of any disease that can cause renal tubular acidosis.

• Arterial blood gas
• Serum electrolytes
• Urine pH

Arterial blood gas analysis or a serum electrolytes test (such as a basic metabolic panel) will confirm acidosis is present and determine whether it is respiratory acidosis or metabolic acidosis.

Other tests may be needed to determine the cause of the acidosis.

Treatment is aimed at the underlying condition. In certain circumstances, sodium bicarbonate (baking soda) may be given to improve the acidity of the blood.

Directions to Hospitals Treating Metabolic acidosis

What can be expected will depend on the underlying disease causing the renal tubular acidosis.

When very severe, acidosis can lead to shock or death.

Keeping type 1 diabetes under control may help prevent diabetic ketoacidosis, one type of metabolic acidosis.

http://www.nlm.nih.gov/medlineplus/ency/article/000335.htm

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