
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Respiratory failure classification
Introduction
Overview
Overview
Respiratory failure may be classified into several subtypes as follows; Type I, Type II, Type III, Type IV.
Classification
Classification
The classification of respiratory failure is as follows:[1]
 |  |  |  |  |  | Respiratory Failure |  |  |  | ||||||||||||||||||||||
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | |||||||||||||
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ||||||||||||||||
| Type I | Â | Type II | Â | Type III | Â | Type IV | |||||||||||||||||||||||||
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ||||||||||||
| Hypoxemic | Â | Hypercapnic | Â | Peri-operative | Â | Shock | |||||||||||||||||||||||||
Classification based on A-a gradient
Respiratory failure patients may have a normal or increased A-a gradient depending upon the etiology of the respiratory failure. The following table outlines the major characteristics:
 |  |  |  |  |  |  |  |  |  | Respiratory Failure-decreased SaO2 |  |  |  | ||||||||||||||||||||||||||||||||||
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | |||||||||||||||||||||||||||
 |  |  |  |  |  |  |  |  |  |  |  |  | |||||||||||||||||||||||||||||||||||
 |  |  |  |  |  | Normal A-a gradient |  |  |  |  |  |  |  | Increased A-a gradient | |||||||||||||||||||||||||||||||||
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ||||||||||||||||||||
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ||||||||||||||||||||||||||||||||
 |  |  | Normal PaCO2 |  |  |  | Increased PaCO2 |  | Hypoxemia does not correct with 100% O2 |  |  |  |  | Hypoxemia corrects with 100% O2 | |||||||||||||||||||||||||||||||||
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | |||||||||||||||||||||
 |  |  | Decreased FiO2 or decreased PiO2 |  |  |  | Hypoventilation (sedation, COPD, asthma, diaphragmatic paralysis or Neuromuscular disease) |  |  | True shunt (Left to right shunts, CHF, pneumonia, atelectasis) |  |  |  | Vascular disease (pulmonary embolism), airway disease (COPD, asthma), alveolar filling (CHF, pneumonia) | |||||||||||||||||||||||||||||||||
References
References
- ↑ Hall, Jesse (2015). “CHAPTER 43: The Pathophysiology and Differential Diagnosis of Acute Respiratory Failure”. Principles of critical care. New York: McGraw-Hill Education. ISBN 0071738819.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2]
