Other diagnostic studies for retinoblastoma include fluorescein angiography and electroretinogram.

• This imaging study can be used to differentiate retinoblastoma from other lesions.^[1]
• Fluorescein angiography is particularly helpful in differentiating the tumor from the advanced form of Coats’s disease.
• Imaging findings associated with the diagnosis of retinoblastoma include:
  • Normal filling of enlarged dilated vessels entering a hyper- and hypo-fluorescent tumor mass

• Electroretinogram may be helpful in treatment and monitoring of retinoblastoma. It may be used for:^[2]
  • Monitoring retinal function during treatment
  • Obtaining information about visual potential in pre-verbal children
  • Observing the effect of treatment toxicity on retinal function

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