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Rickets

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords:

Overview

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Rickets is a softening of the bones in children potentially leading to fractures and deformity. Rickets is among the most frequent childhood diseases in many developing countries. The predominant cause is a vitamin D deficiency, but lack of adequate calcium in the diet may also lead to rickets. Although it can occur in adults, the majority of cases occur in children suffering from severe malnutrition, usually resulting from famine or starvation during the early stages of childhood. Osteomalacia is the term used to describe a similar condition occurring in adults, generally due to a deficiency of vitamin D.

The origin of the word “rickets” is unknown. The Greek derived word “rachitis” (meaning “inflammation of the spine”) was later adopted as the scientific term for rickets, due chiefly to the words’ similarity in sound.

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Type chapter name here from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Surgery

Medical Therapy

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

References

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Historical Perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Historical Perspective

References

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Classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Classification

References

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Pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Pathophysiology

References

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Causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Causes

References

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Differentiating Any Disease from other Diseases

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Differentiating Rickets from other Diseases

References

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Epidemiology and Demographics

Overview

Rickets is a softening of the bones in children potentially leading to fractures and deformity. Rickets is among the most frequent childhood diseases in many developing countries. The predominant cause is a vitamin D deficiency, but lack of adequate calcium in the diet may also lead to rickets. Although it can occur in adults, the majority of cases occur in children suffering from severe malnutrition, usually resulting from famine or starvation during the early stages of childhood. Osteomalacia is the term used to describe a similar condition occurring in adults, generally due to a deficiency of vitamin D. The origin of the word “rickets” is unknown. The Greek derived word “rachitis” (meaning “inflammation of the spine”) was later adopted as the scientific term for rickets, due chiefly to the words’ similarity in sound.

Epidemiology

Those at higher risk for developing rickets include:

  • Breast-fed infants whose mothers are not exposed to sunlight
  • Breast-fed infants who are not exposed to sunlight
  • Individuals not consuming fortified milk, such as those who are lactose intolerant

Individuals with red hair have a decreased risk for rickets due to their greater production of vitamin D in sunlight.[1]

“rachitis” The “wrist widening” of rickets















References

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Risk Factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Risk Factors

References

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Screening

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Screening

References

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Natural History, Complications and Prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Natural History

Complications

Prognosis

References

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Diagnosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram |Chest X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case Studies

Case #1

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