Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Rizatriptan contraindications
Introduction
Contraindications
Contraindications
MAXALT is contraindicated in patients with:
- Ischemic coronary artery disease (angina pectoris, history of myocardial infarction, or documented silent ischemia), or other significant underlying cardiovascular disease [see Warnings and Precautions (5.1)].
- Coronary artery vasospasm including Prinzmetal’s angina [see Warnings and Precautions (5.1)].
- History of stroke or transient ischemic attack (TIA) [see Warnings and Precautions (5.4)].
- Peripheral vascular disease (PVD) [see Warnings and Precautions (5.5)].
- Ischemic bowel disease [see Warnings and Precautions (5.5)].
- Uncontrolled hypertension [see Warnings and Precautions (5.8)].
- Recent use (i.e., within 24 hours) of another 5-HT1 agonist, ergotamine-containing medication, or ergot-type medication (such as dihydroergotamine or methysergide) [see Drug Interactions (7.2 and 7.3)].
- Hemiplegic or basilar migraine [see Indications and Usage (1)].
- Concurrent administration or recent discontinuation (i.e., within 2 weeks) of a MAO-A inhibitor [see Drug Interactions (7.5) and Clinical Pharmacology (12.3)].
- Hypersensitivity to MAXALT or MAXALT-MLT (angioedema and anaphylaxis seen) [see Adverse Reactions (6.2)].[1]
References
References
Adapted from the FDA Package Insert.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]