Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Roxatidine
Introduction
Overview
Overview
Roxatidine acetate is a specific and competitive histamine H2 receptor antagonist drug that is used to treat gastric ulcers, Zollinger–Ellison syndrome, erosive esophagitis, gastro-oesophageal reflux disease, and gastritis.[1][2]
Pharmacodynamic studies showed that 150Â mg of roxatidine acetate were optimal in suppressing gastric acid secretion, and that a single bedtime dose of 150Â mg was more effective than a dose of 75Â mg twice daily in terms of inhibiting nocturnal acid secretion.[1]
It is available in countries including China, Japan, Korea, Germany, Italy, the Netherlands, Greece and South Africa.[2]
References
References
- ↑ 1.0 1.1 Murdoch D, McTavish D (1991). “Roxatidine acetate. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic potential in peptic ulcer disease and related disorders”. Drugs. 42 (2): 240–260. doi:10.2165/00003495-199142020-00006. PMID 1717223.
- ↑ 2.0 2.1 BioSpectrum Bureau 1 November 2012 Sinhuan’s generic heart drug gets production approval
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]