Health Dictionary Find a Doctor

SGPL1

Sphingosine-1-phosphate lyase 1 is an enzyme that in humans is encoded by the SGPL1 gene.[1][2][3]


References

References

  1. Zhou J, Saba JD (Mar 1998). “Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast”. Biochem Biophys Res Commun. 242 (3): 502–7. doi:10.1006/bbrc.1997.7993. PMID 9464245.
  2. Oskouian B, Sooriyakumaran P, Borowsky AD, Crans A, Dillard-Telm L, Tam YY, Bandhuvula P, Saba JD (Nov 2006). “Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer”. Proc Natl Acad Sci U S A. 103 (46): 17384–9. doi:10.1073/pnas.0600050103. PMC 1859938. PMID 17090686.
  3. “Entrez Gene: SGPL1 sphingosine-1-phosphate lyase 1”.
Further reading

Further reading



Looking for the patient version?

Back to the patient-friendly article

© 2026 MyEClinic – IFTM Institut für Telematik in der Medizin GmbH