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SLC1A4
Introduction
Neutral amino acid transporter A is a protein that in humans is encoded by the SLC1A4 gene.[1][2][3]
In melanocytic cells SLC1A4 gene expression may be regulated by MITF.[4]
References
References
- ↑ Hofmann K, Duker M, Fink T, Lichter P, Stoffel W (Apr 1995). “Human neutral amino acid transporter ASCT1: structure of the gene (SLC1A4) and localization to chromosome 2p13-p15”. Genomics. 24 (1): 20–6. doi:10.1006/geno.1994.1577. PMID 7896285.
- ↑ Zerangue N, Kavanaugh MP (Dec 1996). “ASCT-1 is a neutral amino acid exchanger with chloride channel activity”. J Biol Chem. 271 (45): 27991–4. doi:10.1074/jbc.271.45.27991. PMID 8910405.
- ↑ “Entrez Gene: SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4”.
- ↑ Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). “Novel MITF targets identified using a two-step DNA microarray strategy”. Pigment Cell Melanoma Res. 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971.
Further reading
Further reading
- Arriza JL, Kavanaugh MP, Fairman WA, et al. (1993). “Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family”. J. Biol. Chem. 268 (21): 15329–32. PMID 8101838.
- Maruyama K, Sugano S (1994). “Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides”. Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Shafqat S, Tamarappoo BK, Kilberg MS, et al. (1993). “Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters”. J. Biol. Chem. 268 (21): 15351–5. PMID 8340364.
- Tamarappoo BK, McDonald KK, Kilberg MS (1996). “Expressed human hippocampal ASCT1 amino acid transporter exhibits a pH-dependent change in substrate specificity”. Biochim. Biophys. Acta. 1279 (2): 131–6. doi:10.1016/0005-2736(95)00259-6. PMID 8603078.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). “Construction and characterization of a full length-enriched and a 5′-end-enriched cDNA library”. Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Marin M, Tailor CS, Nouri A, Kabat D (2000). “Sodium-dependent neutral amino acid transporter type 1 is an auxiliary receptor for baboon endogenous retrovirus”. J. Virol. 74 (17): 8085–93. doi:10.1128/JVI.74.17.8085-8093.2000. PMC 112341. PMID 10933718.
- Younes M, Pathak M, Finnie D, et al. (2001). “Expression of the neutral amino acids transporter ASCT1 in esophageal carcinomas”. Anticancer Res. 20 (5C): 3775–9. PMID 11268453.
- Pinilla J, Barber A, Lostao MP (2002). “Active transport of alanine by the neutral amino-acid exchanger ASCT1”. Can. J. Physiol. Pharmacol. 79 (12): 1023–9. doi:10.1139/cjpp-79-12-1023. PMID 11824937.
- Lavillette D, Marin M, Ruggieri A, et al. (2002). “The envelope glycoprotein of human endogenous retrovirus type W uses a divergent family of amino acid transporters/cell surface receptors”. J. Virol. 76 (13): 6442–52. doi:10.1128/JVI.76.13.6442-6452.2002. PMC 136247. PMID 12050356.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Marin M, Lavillette D, Kelly SM, Kabat D (2003). “N-linked glycosylation and sequence changes in a critical negative control region of the ASCT1 and ASCT2 neutral amino acid transporters determine their retroviral receptor functions”. J. Virol. 77 (5): 2936–45. doi:10.1128/JVI.77.5.2936-2945.2003. PMC 149750. PMID 12584318.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Hillier LW, Graves TA, Fulton RS, et al. (2005). “Generation and annotation of the DNA sequences of human chromosomes 2 and 4”. Nature. 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
- Chi A, Valencia JC, Hu ZZ, et al. (2007). “Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes”. J. Proteome Res. 5 (11): 3135–44. doi:10.1021/pr060363j. PMID 17081065.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.