Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
SPACA3
Introduction
Sperm acrosome membrane-associated protein 3 is a protein that in humans is encoded by the SPACA3 gene. It may be involved in adhesion to the egg before the egg is fertilized.[1][2]
References
References
- ↑ Mandal A, Klotz KL, Shetty J, Jayes FL, Wolkowicz MJ, Bolling LC, Coonrod SA, Black MB, Diekman AB, Haystead TA, Flickinger CJ, Herr JC (Apr 2003). “SLLP1, a unique, intra-acrosomal, non-bacteriolytic, c lysozyme-like protein of human spermatozoa”. Biol Reprod. 68 (5): 1525–37. doi:10.1095/biolreprod.102.010108. PMID 12606493.
- ↑ “Entrez Gene: SPACA3 sperm acrosome associated 3”.
Further reading
Further reading
- Niyonsaba F, Ogawa H (2006). “Protective roles of the skin against infection: implication of naturally occurring human antimicrobial agents beta-defensins, cathelicidin LL-37 and lysozyme”. J. Dermatol. Sci. 40 (3): 157–68. doi:10.1016/j.jdermsci.2005.07.009. PMID 16150577.
- Cramer EM, Breton-Gorius J (1987). “Ultrastructural localization of lysozyme in human neutrophils by immunogold”. J. Leukoc. Biol. 41 (3): 242–7. PMID 3470418.
- Welsh IR, Spitznagel JK (1973). “Distribution of lysosomal enzymes, cationic proteins, and bactericidal substances in subcellular fractions of human polymorphonuclear leukocytes”. Infect. Immun. 4 (2): 97–102. PMC 416271. PMID 5154881.
- Ibrahim HR, Matsuzaki T, Aoki T (2001). “Genetic evidence that antibacterial activity of lysozyme is independent of its catalytic function”. FEBS Lett. 506 (1): 27–32. doi:10.1016/S0014-5793(01)02872-1. PMID 11591365.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Clark HF, Gurney AL, Abaya E, et al. (2003). “The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment”. Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
- Wang Z, Zhang Y, Mandal A, et al. (2005). “The spermatozoa protein, SLLP1, is a novel cancer-testis antigen in hematologic malignancies”. Clin. Cancer Res. 10 (19): 6544–50. doi:10.1158/1078-0432.CCR-04-0911. PMID 15475442.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Zhang K, Gao R, Zhang H, et al. (2006). “Molecular cloning and characterization of three novel lysozyme-like genes, predominantly expressed in the male reproductive system of humans, belonging to the c-type lysozyme/alpha-lactalbumin family”. Biol. Reprod. 73 (5): 1064–71. doi:10.1095/biolreprod.105.041889. PMID 16014814.