
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
SPRR2A
Introduction
Small proline-rich protein 2A is a protein that in humans is encoded by the SPRR2A gene.[1][2]
References
References
- ↑ Gibbs S, Fijneman R, Wiegant J, van Kessel AG, van De Putte P, Backendorf C (Aug 1993). “Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins”. Genomics. 16 (3): 630–7. doi:10.1006/geno.1993.1240. PMID 8325635.
- ↑ “Entrez Gene: SPRR2A small proline-rich protein 2A”.
Further reading
Further reading
- Gregory SG, Barlow KF, McLay KE, et al. (2006). “The DNA sequence and biological annotation of human chromosome 1”. Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
- Tong L, Corrales RM, Chen Z, et al. (2006). “Expression and Regulation of Cornified Envelope Proteins in Human Corneal Epithelium”. Invest. Ophthalmol. Vis. Sci. 47 (5): 1938–46. doi:10.1167/iovs.05-1129. PMC 2906387. PMID 16639001.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). “The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Hong SH, Nah HY, Lee JY, et al. (2004). “Estrogen regulates the expression of the small proline-rich 2 gene family in the mouse uterus”. Mol. Cells. 17 (3): 477–84. PMID 15232223.
- Cabral A, Fischer DF, Vermeij WP, Backendorf C (2003). “Distinct functional interactions of human Skn-1 isoforms with Ese-1 during keratinocyte terminal differentiation”. J. Biol. Chem. 278 (20): 17792–9. doi:10.1074/jbc.M300508200. PMID 12624109.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). “Shotgun sequencing of the human transcriptome with ORF expressed sequence tags”. Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.
- Fischer DF, van Drunen CM, Winkler GS, et al. (1999). “Involvement of a nuclear matrix association region in the regulation of the SPRR2A keratinocyte terminal differentiation marker”. Nucleic Acids Res. 26 (23): 5288–94. doi:10.1093/nar/26.23.5288. PMC 147987. PMID 9826750.
- Steinert PM, Marekov LN (1997). “Direct evidence that involucrin is a major early isopeptide cross-linked component of the keratinocyte cornified cell envelope”. J. Biol. Chem. 272 (3): 2021–30. doi:10.1074/jbc.272.3.2021. PMID 8999895.
- Fischer DF, Gibbs S, van De Putte P, Backendorf C (1996). “Interdependent transcription control elements regulate the expression of the SPRR2A gene during keratinocyte terminal differentiation”. Mol. Cell. Biol. 16 (10): 5365–74. PMC 231535. PMID 8816448.
- Gibbs S, Lohman F, Teubel W, et al. (1990). “Characterization of the human spr2 promoter: induction after UV irradiation or TPA treatment and regulation during differentiation of cultured primary keratinocytes”. Nucleic Acids Res. 18 (15): 4401–7. doi:10.1093/nar/18.15.4401. PMC 331257. PMID 2388825.
