
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
ST6GALNAC6
Introduction
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 is an enzyme that in humans is encoded by the ST6GALNAC6 gene.[1][2]
References
References
- ↑ Tsuchida A, Okajima T, Furukawa K, Ando T, Ishida H, Yoshida A, Nakamura Y, Kannagi R, Kiso M, Furukawa K (Jun 2003). “Synthesis of disialyl Lewis a (Le(a)) structure in colon cancer cell lines by a sialyltransferase, ST6GalNAc VI, responsible for the synthesis of alpha-series gangliosides”. J Biol Chem. 278 (25): 22787–94. doi:10.1074/jbc.M211034200. PMID 12668675.
- ↑ “Entrez Gene: ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6”.
Further reading
Further reading
- Senda M, Ito A, Tsuchida A, et al. (2007). “Identification and expression of a sialyltransferase responsible for the synthesis of disialylgalactosylgloboside in normal and malignant kidney cells: downregulation of ST6GalNAc VI in renal cancers”. Biochem. J. 402 (3): 459–70. doi:10.1042/BJ20061118. PMC 1863573. PMID 17123352.
- Lim J, Hao T, Shaw C, et al. (2006). “A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration”. Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
- Harduin-Lepers A, Mollicone R, Delannoy P, Oriol R (2005). “The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach”. Glycobiology. 15 (8): 805–17. doi:10.1093/glycob/cwi063. PMID 15843597.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Clark HF, Gurney AL, Abaya E, et al. (2003). “The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment”. Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Okajima T, Chen HH, Ito H, et al. (2000). “Molecular cloning and expression of mouse GD1alpha/GT1aalpha/GQ1balpha synthase (ST6GalNAc VI) gene”. J. Biol. Chem. 275 (10): 6717–23. doi:10.1074/jbc.275.10.6717. PMID 10702226.
