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STMN3

Introduction

Stathmin-3 is a protein that in humans is encoded by the STMN3 gene.[1][2][3]

Function

Function

The protein encoded by this gene belongs to the stathmin/oncoprotein 18 family of microtubule-destabilizing phosphoproteins. It is similar to the SCG10 protein and is involved in signal transduction and regulation of microtubule dynamics.[3]

Interactions

Interactions

STMN3 has been shown to interact with TRPC5.[4]

References

References

  1. ↑ Ozon S, Byk T, Sobel A (June 1998). “SCLIP: a novel SCG10-like protein of the stathmin family expressed in the nervous system”. Journal of Neurochemistry. 70 (6): 2386–96. doi:10.1046/j.1471-4159.1998.70062386.x. PMIDΒ 9603203.
  2. ↑ Bai C, Connolly B, Metzker ML, Hilliard CA, Liu X, Sandig V, Soderman A, Galloway SM, Liu Q, Austin CP, Caskey CT (February 2000). “Overexpression of M68/DcR3 in human gastrointestinal tract tumors independent of gene amplification and its location in a four-gene cluster”. Proceedings of the National Academy of Sciences of the United States of America. 97 (3): 1230–5. doi:10.1073/pnas.97.3.1230. PMCΒ 15578. PMIDΒ 10655513.
  3. ↑ 3.0 3.1 “Entrez Gene: STMN3 stathmin-like 3”.
  4. ↑ Greka A, Navarro B, Oancea E, Duggan A, Clapham DE (August 2003). “TRPC5 is a regulator of hippocampal neurite length and growth cone morphology”. Nature Neuroscience. 6 (8): 837–45. doi:10.1038/nn1092. PMIDΒ 12858178.
Further reading

Further reading

  • Gavet O, Ozon S, Manceau V, Lawler S, Curmi P, Sobel A (November 1998). “The stathmin phosphoprotein family: intracellular localization and effects on the microtubule network”. Journal of Cell Science. 111 ( Pt 22) (22): 3333–46. PMIDΒ 9788875.
  • Charbaut E, Curmi PA, Ozon S, Lachkar S, Redeker V, Sobel A (May 2001). “Stathmin family proteins display specific molecular and tubulin binding properties”. The Journal of Biological Chemistry. 276 (19): 16146–54. doi:10.1074/jbc.M010637200. PMIDΒ 11278715.
  • BiΓ¨che I, Maucuer A, Laurendeau I, Lachkar S, Spano AJ, Frankfurter A, LΓ©vy P, Manceau V, Sobel A, Vidaud M, Curmi PA (April 2003). “Expression of stathmin family genes in human tissues: non-neural-restricted expression for SCLIP”. Genomics. 81 (4): 400–10. doi:10.1016/S0888-7543(03)00031-4. PMIDΒ 12676564.
  • Greka A, Navarro B, Oancea E, Duggan A, Clapham DE (August 2003). “TRPC5 is a regulator of hippocampal neurite length and growth cone morphology”. Nature Neuroscience. 6 (8): 837–45. doi:10.1038/nn1092. PMIDΒ 12858178.