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Hay fever

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Seasonal rhinitis, allergic rhinitis, seasonal allergic rhinitis, intermittent rhinitis

Overview

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Hay fever is caused by pollens of specific seasonal plants and airborne chemicals and dust particles in people who are allergic to these substances. It is characterised by sneezing, runny nose and itching eyes. This seasonal allergic rhinitis is commonly known as ‘hay fever’, because it is most prevalent during haying season. It is particularly prevalent from late May to the end of June (in the Northern Hemisphere). However it is possible to suffer from hayfever throughout the year

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Historical Perspective

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Classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Classification

The two categories of allergic rhinitis include:

  • Seasonal – occurs particularly during pollen seasons. Seasonal allergic rhinitis does not usually develop until after 6 years of age.
  • Perennial – occurs throughout the year. This type of allergic rhinitis is commonly seen in younger children.[1]

References

  1. “Rush University Medical Center”. Retrieved 2008-03-05.

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Pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Pathophysiology

As noted above, hay fever involves an allergic reaction to pollen. A virtually identical reaction occurs with allergy to mold, animal dander, dust and similar inhaled allergens. Particulate matter in polluted air and chemicals such as chlorine and detergents, which can normally be tolerated, can greatly aggravate the condition.

When an allergen such as pollen or dust is inhaled by a person with a sensitized immune system, it triggers antibody production. These antibodies mostly bind to mast cells, which contain histamine. When the mast cells are stimulated by pollen and dust, histamine (and other chemicals) are released. This causes itching, swelling, and mucus production. Symptoms vary in severity from person to person. Very sensitive individuals can experience hives or other rashes.

Some disorders may be associated with allergies, which are common. Heredity and environmental exposures may contribute to a predisposition to allergies. These include eczema and asthma, among others.

The time of year at which hay fever symptoms manifest themselves varies greatly depending on the types of pollen to which an allergic reaction is produced. The pollen count, in general, is highest from mid-spring to early summer. As most pollens are produced at fixed periods in the year, a long-term hay fever sufferer may also be able to anticipate when the symptoms are most likely to begin and end, although this may be complicated by an allergy to dust particles.

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Causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Causes

The pollens that cause hay fever vary from person to person and from region to region; generally speaking, the tiny, hardly visible pollens of Anemophily (wind-pollinated) plants are the predominant culprits. Pollens of entomophily (insect-pollinated) plants are too large to remain airborne and pose no risk. Examples of plants commonly responsible for hay fever include:

  • Trees: Such as birch (Betula), alder (Alnus), hazel (Corylus), hornbeam (Carpinus), horse chestnut (Aesculus), willow (Salix), poplar (Populus), plane (Platanus), linden/lime (Tilia) and olive (Olea). In northern latitudes birch is considered to be the most important allergenic tree pollen, with an estimated 15–20% of hay fever sufferers sensitive to birch pollen grains. Olive pollen is most predominant in Mediterranean regions.
  • Grasses (Family Poaceae): Especially ryegrass (Lolium sp.) and Timothy-grass (Phleum pratense). An estimated 90% of hay fever sufferers are allergic to grass pollen.
  • Weeds: Ragweed (Ambrosia), plantain (Plantago), nettle/parietaria (Urticaceae), mugwort (Artemisia), Fat hen (Chenopodium) and sorrel/dock (Rumex)
  • Drugs: Prednisolone

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Differentiating Hay fever from other Diseases

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Epidemiology and Demographics

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Risk Factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Risk Factors

In addition to individual sensitivity and geographic differences in local plant populations, the amount of pollen in the air can be a factor in whether hay fever symptoms develop. Hot, dry, windy days are more likely to have increased amounts of pollen in the air than cool, damp, rainy days when most pollen is washed to the ground.Whether or not you are likely to develop allergies is often passed down through families. If both your parents have allergies, you are likely to have allergies. The chance is greater if your mother has allergies.

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Screening

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Natural History, Complications and Prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Natural History, Complications and Prognosis

Complications

Prognosis

Most symptoms of allergic rhinitis can be readily treated.

In some cases (particularly in children), people may outgrow an allergy as the immune system becomes less sensitive to the allergen. However, as a general rule, once a substance causes allergies for an individual, it can continue to affect the person over the long term.

More severe cases of allergic rhinitis require immunotherapy (allergy shots) or removal of tissue in the nose (e.g., nasal polyps) or sinuses. A case-control study found “symptomatic allergic rhinitis and rhinitis medication use are associated with a significantly increased risk of unexpectedly dropping a grade in summer examinations”.[1]

References

  1. Walker S, Khan-Wasti S, Fletcher M, Cullinan P, Harris J, Sheikh A (2007). “Seasonal allergic rhinitis is associated with a detrimental effect on examination performance in United Kingdom teenagers: case-control study”. J. Allergy Clin. Immunol. 120 (2): 381–7. doi:10.1016/j.jaci.2007.03.034. PMID 17560637.

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Diagnosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory tests | Other Diagnostic Studies

Treatment

Treatment

Medical Therapy | Alternative Therapy | Primary Prevention | Secondary Prevention | Cost Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case Studies

Case #1

External Links

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ca:Rinitis al·lèrgica cs:Alergická rýma cy:Clefyd y gwair de:Allergische Rhinitis it:Raffreddore allergico lt:Šienligė nl:Hooikoorts no:Pollenallergi sv:Pollenallergi

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