Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Shigellosis other diagnostic studies
Introduction
Overview
Overview
Other diagnostic studies, such as enzyme-linked immunoassay (ELISA), polymerase chain reaction (PCR), or colon/rectal biopsies, are not always necessary but may be required for the diagnosis of shigellosis in the minority of patients, such as high risk patients who are hospitalized and in need of urgent management).
Other Diagnostic Studies
Other Diagnostic Studies
Enzyme-linked Immunoassay (ELISA)
- Detection of S. dysenteriae type 1 toxin in stools
Polymerase Chain Reaction (PCR)
- Detection of virulence genes of Shigella
- ipaH gene
- virF gene
- virA gene
Colonic or Rectal Biopsy
On microscopic histopathological analysis, the following findings may be observed from samples of the colon, rectum, and occasionally the distal ileum:
- PMN infiltration
- Formation of patchy inflammatory pseudomembrane
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-In-Chief: Yazan Daaboul; Serge Korjian