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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Sickle-cell disease risk factors

Introduction

Overview

Overview

The most potent risk factor in the development of sickle-cell disease is race.

Risk Factors

Risk Factors

Common Risk Factors

  • Common risk factors in the development of sickle-cell disease include:[1][2]
    • Africans
    • African Americans
    • Indians
    • Mediterranean descent
    • Geographic location
References

References

  1. ↑ Makani J, Ofori-Acquah SF, Nnodu O, Wonkam A, Ohene-Frempong K (2013). “Sickle cell disease: new opportunities and challenges in Africa”. ScientificWorldJournal. 2013: 193252. doi:10.1155/2013/193252. PMC 3988892. PMID 25143960.
  2. ↑ Grosse SD, Odame I, Atrash HK, Amendah DD, Piel FB, Williams TN (December 2011). “Sickle cell disease in Africa: a neglected cause of early childhood mortality”. Am J Prev Med. 41 (6 Suppl 4): S398–405. doi:10.1016/j.amepre.2011.09.013. PMC 3708126. PMID 22099364.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shyam Patel [2]