Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Sideroblastic anemia physical examination
Introduction
Overview
Overview
Patients usually presents with signs of anemia with pale skin, dyspnea, and tachycardia. Growth retardation is seen in children. Other signs include hypothermia, lead line on teeth margins, photosensitivity, petechiae, optic atrophy, ataxia, and incoordination. Hepatosplenomegaly is common patients with iron overload.
Physical Examination
Physical Examination
Patients with sideroblastic anemia may exibit following signs.[1]
Appearance of the Patient
- Patients with sideroblastic anemia usually appear pale
- Growth retardation in children
Vital Signs
Skin
HEENT
- HEENT examination of patients with sideroblastic anemia is usually normal except:
- Oral – Lead line on teeth margins
- Eyes – Optic atrophy (associated with DIDMOAD syndrome)
Neck
Lungs
Heart
- Arrhythmias
- Heart failure
- Chest pain
- S3 gallop
Abdomen
Back
- Back examination of patients with sideroblastic anemia is usually normal
Genitourinary
- Genitourinary examination of patients with sideroblastic anemia is usually normal except:
- Pink staining of diapers in childrens from porphyrins in urine
Neuromuscular
Extremities
- Extremities examination of patients with sideroblastic anemia is usually normal
References
References
- ↑ Cazzola M, Malcovati L (2015). “Diagnosis and treatment of sideroblastic anemias: from defective heme synthesis to abnormal RNA splicing”. Hematology Am Soc Hematol Educ Program. 2015: 19–25. doi:10.1182/asheducation-2015.1.19. PMID 26637696.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2] Associate Editor(s)-in-Chief: Nazia Fuad M.D.