Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Sideroblastic anemia surgery
Introduction
Overview
Overview
In severe cases, bone marrow transplant is the only option with limited information about the success rate.
Indications
Indications
- Surgery is not the first-line treatment option for patients with sideroblastic anemia.[1]
- The indications for surgery are:
- Young patients with congenital sideroblastic anemia, not responsive to pyridoxine
- Transfusion dependent patients
- Liver cirrhosis
- Iron overload refractory to iron chelation therapy
- Iron overload refractory to phlebotomy
Contraindications
Contraindications
- Patients with organ damage from secondary hemochromatosis
- Poor surgical candidacy
References
References
- ↑ Rouault TA (June 2016). “Mitochondrial iron overload: causes and consequences”. Curr. Opin. Genet. Dev. 38: 31–37. doi:10.1016/j.gde.2016.02.004. PMC 5035716. PMID 27026139.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nazia Fuad M.D.