The goals of research on diseases such as Sjögren’s syndrome focus on increasing knowledge and understanding of the disorder, improving diagnostic techniques, and finding ways to treat, prevent, and cure the disorder.

Many scientists are working on developing an animal model of Sjögren’s syndrome. Dr Hal Scofield’s lab at Oklahoma Medical Research Foundation have developed an animal model by immunizing mice with 60 kD Ro peptide. Days after immunization, salivary flow was decreased and lymphocyte infiltrates as well as salivary dysfunction was observed which are highly reminiscent of human Sjögren’s syndrome.