Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Sjögren's syndrome laboratory findings
Introduction
Overview
Overview
Laboratory findings consistent with the diagnosis of Sjögren’s syndrome include elevated erythrocyte sedimentation rate (ESR), cytopenia, and presence of anti-SSA/Ro and anti-SSB/La.
Laboratory Findings
Laboratory Findings
- Laboratory findings consistent with the diagnosis of Sjögren’s syndrome include:[1][2][3][4]
- Elevated erythrocyte sedimentation rate (ESR)
- Anemia
- Leukopenia
- Thrombocytopenia
- Eosinophilia
- Hypergammaglobulinemia
- Presence of anti-SSA/Ro, anti-SSB/La
- Presence of rheumatoid factor (RF)
- Presence of anti–alpha-fodrin antibody (diagnostic marker of juvenile Sjögren’s syndrome)
- Increasing creatinine (Cr) level
- Proteinuria
- Urinary casts
- Hematuria
References
References
- ↑ Ramos-Casals M, Brito-Zerón P, Solans R, Camps MT, Casanovas A, Sopeña B, Díaz-López B, Rascón FJ, Qanneta R, Fraile G, Pérez-Alvarez R, Callejas JL, Ripoll M, Pinilla B, Akasbi M, Fonseca E, Canora J, Nadal ME, de la Red G, Fernández-Regal I, Jiménez-Heredia I, Bosch JA, Ayala MD, Morera-Morales L, Maure B, Mera A, Ramentol M, Retamozo S, Kostov B (February 2014). “Systemic involvement in primary Sjogren’s syndrome evaluated by the EULAR-SS disease activity index: analysis of 921 Spanish patients (GEAS-SS Registry)”. Rheumatology (Oxford). 53 (2): 321–31. doi:10.1093/rheumatology/ket349. PMID 24162151.
- ↑ Yazdany J, Schmajuk G, Robbins M, Daikh D, Beall A, Yelin E, Barton J, Carlson A, Margaretten M, Zell J, Gensler LS, Kelly V, Saag K, King C (March 2013). “Choosing wisely: the American College of Rheumatology’s Top 5 list of things physicians and patients should question”. Arthritis Care Res (Hoboken). 65 (3): 329–39. doi:10.1002/acr.21930. PMC 4106486. PMID 23436818.
- ↑ Beckman KA, Luchs J, Milner MS (2016). “Making the diagnosis of Sjögren’s syndrome in patients with dry eye”. Clin Ophthalmol. 10: 43–53. doi:10.2147/OPTH.S80043. PMC 4699514. PMID 26766898.
- ↑ Both T, Dalm VA, van Hagen PM, van Daele PL (2017). “Reviewing primary Sjögren’s syndrome: beyond the dryness – From pathophysiology to diagnosis and treatment”. Int J Med Sci. 14 (3): 191–200. doi:10.7150/ijms.17718. PMC 5370281. PMID 28367079.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]