Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Small intestine cancer risk factors
Introduction
Overview
Overview
Common risk factors in the development of small intestine cancer are Crohn’s disease, celiac disease, radiation exposure, hereditary cancer syndromes, smoking, and alcohol.
Risk Factors
Risk Factors
- There are no established risk factors of small intestinal cancers.
- However, there are some associations and most common association is Crohn’s disease.
- Other associated factors are described below.
Common risk factors
- Crohn disease is considered to be the most important risk factor of small intestinal cancers.[1]
Less common risk factors
- Other associated risk factors are:[2][3]
- Familial Adenomatous Polyposis (FAP)
- Lynch syndrome
- Acquired immunodeficiency syndrome (AIDS)
- Celiac disease
- Peutz-Jeghers Syndrome
- Hereditary nonpolyposis colorectal neoplasms
- Radiation exposure
- Hereditary cancer syndromes
- Familial adenomatous polyposis
- Hereditary nonpolyposis colorectal cancer
- Peutz-Jeghers syndrome
- MUTYH-associated polyposis
- Smoking and alcohol use increases the risk of small intestine cancer
- Colon cancer: Survivors of colon cancer have an increased risk of getting cancer of the small intestine
References
References
- ↑ Dabaja BS, Suki D, Pro B, Bonnen M, Ajani J (August 2004). “Adenocarcinoma of the small bowel: presentation, prognostic factors, and outcome of 217 patients”. Cancer. 101 (3): 518–26. doi:10.1002/cncr.20404. PMID 15274064.
- ↑ Sarosiek T, Stelmaszuk M (February 2018). “[Small intestine neoplasms]”. Pol. Merkur. Lekarski (in Polish). 44 (260): 45–48. PMID 29498365.
- ↑ Delaunoit T, Neczyporenko F, Limburg PJ, Erlichman C. Pathogenesis and risk factors of small bowel adenocarcinoma: a colorectal cancer sibling? Am J Gastroenterol. 2005 Mar;100(3):703-10. PMID 15743371.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Qurrat-ul-ain Abid, M.D.[2], Parminder Dhingra, M.D. [3]