Sneddon-Wilkinson disease

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Jesus Rosario Hernandez, M.D. [2].

Synonyms and keywords: IgA pemphigus, subcorneal pustular dermatosis.

Overview

IgA pemphigus is a subtype of pemphigus with two distinct forms:

Subcorneal pustular dermatosis (also known as “Sneddon–Wilkinson disease”) (distinct from and not to be confused with subcorneal pustular dermatosis type of IgA pemphigus) is skin condition that is a rare, chronic, recurrent, pustular eruption characterized histopathologically by subcorneal pustules that contain abundant neutrophils.^[1]^[2]^:203
Intraepidermal neutrophilic IgA dermatosis is characterized histologically by intraepidermal bullae with neutrophils, some eosinophils, and acantholysis.^[2]

References

↑ Irwin M. Freedberg; et al., eds. (2003). Fitzpatrick’s dermatology in general medicine (6th ed.). New York, NY [u.a.]: McGraw-Hill. p. 625. ISBN 0-07-138076-0.
↑ ^2.0 ^2.1 James, William; Berger, Timothy; Elston, Dirk (2005). Andrews’ Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.

Overview