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Sommelet reaction

Introduction


The Sommelet reaction is an organic reaction in which a benzyl halide is converted to an aldehyde by action of hexamine and water [1][2][3].

The Sommelet reaction

A conceptually related reaction is the Duff reaction (halide replaced by an arene).

In the Kröhnke aldehyde synthesis [4] the oxidizing reagent is is a combination of pyridine and p-nitrosodimethylaniline.

References

  1. ↑ Marcel Sommelet (1913). “Sur un mode de décomposition des halogénoalcoylates d’hexaméthylène – tétramine”. Compt. rend. 157: 852–854. Check date values in: |year= (help)
  2. ↑ Template:JerryMarch
  3. ↑ For an example see: Organic Syntheses, Coll. Vol. 4, p.918 (1963); Vol. 33, p.93 (1953). http://www.orgsynth.org/orgsyn/pdfs/CV4P0918.pdf
  4. ↑ F. Kröhnke, Ber., 71B, 2583 (1938).