Southern tick-associated rash illness history and symptoms

The rash of STARI is a red, expanding “bull’s-eye” lesion that develops around the site of a lone star tick bite. The rash usually appears within 7 days of tick bite and expands to a diameter of 8 centimeters (3 inches) or more. The rash should not be confused with much smaller areas of redness and discomfort that can occur commonly at the site of any tick bite. Patients may also experience fatigue, headache, fever, and muscle pains. The saliva from lone star ticks can be irritating; redness and discomfort at a bite site does not necessarily indicate an infection.

This condition has been named southern tick-associated rash illness (STARI). The rash may sometimes be accompanied by fatigue, headache, fever, and muscle pains. In the cases of STARI studied to date, the rash and accompanying symptoms have resolved following treatment with an oral antibiotic (doxycycline), but it is unknown whether this medication speeds recovery. STARI has not been linked to arthritis, neurologic disease, or chronic symptoms.

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