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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Squamous cell carcinoma of the skin classification

Introduction

Overview

Overview

Classification

Classification

Category Criteria
T – Primary tumor
TX Primary tumor cannot be assessed
Tis Carcinoma in situ
T1 Tumor ≤ to 2 cm
T2 Tumor > 2 cm, and ≤ to 4 cm
T3 Tumor > 4 cm or minor bone erosion or perineural invasion or deep invasion
T4 Tumor with gross cortical bone/marrow, skull base invasion and/or skull base foramen invasion
T4a Tumor with gross cortical bone/marrow invasion
T4b Tumor with skull base invasion and/or skull base foramen involvement
N – Regional lymph nodes
NX Regional lymph nodes cannot be assessed
N0 No regional lymph node metastasis
N1 Metastasis in a single ipsilateral lymph node, tumor size ≤ 3 cm, and no extranodal extension
N2
  • Metastasis in a single ipsilateral lymph node, tumor size ≤ 3 cm, and presence of extranodal extension; or
  • Tumor size > 3 cm but ≤ 6 cm without extranodal extension; or
  • Metastasis in a single ipsilateral lymph node, tumor size ≤ 3 cm, and presence of extranodal extension; or
  • Metastases in multiple ipsilateral lymph nodes, tumor size ≤ 6 cm without extranodal extension; or
  • In bilateral or contralateral lymph node(s), tumor size ≤ 6 cm without extranodal extension
N2a
  • Metastasis in a single ipsilateral lymph node, tumor size ≤ 3 cm, and presence of extranodal involvement; or
  • Single ipsilateral node larger, tumor size > 3 cm and ≤ 6 cm, without extranodal extension
N2b Metastases in multiple ipsilateral nodes, tumor size ≤ 6 cm, and without extranodal extension
N2c Metastases in bilateral or contralateral lymph node(s), tumor size ≤ 6 cm, and without extranodal extension
N3
  • Metastasis in a lymph node, tumor size > 6 cm, and without extranodal extension; or
  • In a single ipsilateral node, tumor size > 3 cm, and presence of extranodal extension; or
  • Multiple ipsilateral, contralateral, or bilateral nodes with any extranodal exension; or
  • Single contralateral node of any size with any extranodal extension
N3a Metastasis in a lymph node, tumor size > 6 cm, and absence of extranodal extension
N3b
  • Metastasis in a single ipsilateral node, tumor size > 3 cm, and in presence of extranodal extension; or
  • Multiple ipsilateral, contralateral, or bilateral nodes, with any extranodal extension; or
  • Single contralateral node of any size and with any extranodal extension
M – Distant metastasis
M0 No distant metastasis
M1 Distant metastasis
References

References


Template:WikiDoc Sources

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Roukoz A. Karam, M.D.[2]