
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Stomach cancer endoscopy and biopsy
Introduction
Overview
Overview
Biopsy may be helpful in the diagnosis of stomach cancer. It has a sensitivity of 98% to diagnose gastric cancer but may be negative in linitis plastica. It is commonly used nowadays as first line of treatment for superficial lesions.
Endoscopy and Biopsy
Endoscopy and Biopsy
- The diagnosis of early lesions appears to be increasing since upper gastrointestinal endoscopy became widely used.
- Obtaining seven biopsies from the ulcer margin and base have a sensitivity of 98% to diagnose gastric cancer.[1]
- It may be false negative in linitis plastica cancers.[2]
- The European guidelines recommend endoscopic resection as a first-line treatment for superficial neoplastic gastric lesions.[3]

References
References
- ↑ Graham DY, Schwartz JT, Cain GD, Gyorkey F (1982). “Prospective evaluation of biopsy number in the diagnosis of esophageal and gastric carcinoma”. Gastroenterology. 82 (2): 228–31. PMID 7054024.
- ↑ Karita M, Tada M (1994). “Endoscopic and histologic diagnosis of submucosal tumors of the gastrointestinal tract using combined strip biopsy and bite biopsy”. Gastrointest Endosc. 40 (6): 749–53. PMID 7859977.
- ↑ Pimentel-Nunes P, Dinis-Ribeiro M, Ponchon T, Repici A, Vieth M, De Ceglie A; et al. (2015). “Endoscopic submucosal dissection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline”. Endoscopy. 47 (9): 829–54. doi:10.1055/s-0034-1392882. PMID 26317585.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
