Health Dictionary

Overview

History and physical examination are the mainstay of diagnosing stomatitis. Laboratory findings can play an important role in diagnosing and differentiating the particular type of stomatitis.

Laboratory findings

History and physical examination are the mainstay of diagnosing stomatitis. If required, laboratory findings can play an important role in diagnosing and differentiating the particular type of stomatitis.

Herpetic Stomatitis

Viral culture
Tzanck smear for active lesions
- It cannot differentiate between the various types of viruses that can cause stomatitis (i.e., HSV-1, HSV-2, or VZV)
Serology
Studies using immunofluorescent techniques
PCR

Noma or Gangrenous stomatitis

The diagnosis of Noma or gangrenous stomatitis is made by:^[1]

Culture for organisms
Biopsy showing deep tissue involvement

Pyostomatitis vegetans

Immunofluorescence testing^[2]
Biopsy (showing hyperplasia of the stratified squamous epithelium)^[3]
Eosinophils, neutrophils, plasma cells and lymphocytes in the connective tissue^[4]
Spongiotic changes^[4]

References

↑ Mandell; Gouglas, Gordon; Bennett, John. Principles and Practice of Infectious Diseases. Harvard Medical School: WILEY MEDICAL. p. 383. ISBN 0-471-87643-7. Unknown parameter |firs1t= ignored (help)
↑ Magliocca KR, Fitzpatrick SG (2017) Autoimmune Disease Manifestations in the Oral Cavity. Surg Pathol Clin 10 (1):57-88. DOI:10.1016/j.path.2016.11.001 PMID: 28153136
↑ Wang H, Qiao S, Zhang X, Liu C (2013). “A case of pyodermatitis-pyostomatitis vegetans”. Am J Med Sci. 345 (2): 168–71. doi:10.1097/MAJ.0b013e31826c5a82. PMID 23138121.
↑ ^4.0 ^4.1 Abellaneda C, Mascaró JM, Vázquez MG, Pablo IM, Iranzo P (2011). “All that glitters is not pemphigus: Pyodermatitis-pyostomatitis vegetans misdiagnosed as IgA pemphigus for 8 years”. Am J Dermatopathol. 33 (1): e1–6. doi:10.1097/DAD.0b013e3181d81ecb. PMID 20689401.

[Gangrenous_stomatitis-1] Mandell; Gouglas, Gordon; Bennett, John. Principles and Practice of Infectious Diseases. Harvard Medical School: WILEY MEDICAL. p. 383. ISBN 0-471-87643-7. Unknown parameter |firs1t= ignored (help)

[pmid28153136-2] Magliocca KR, Fitzpatrick SG (2017) Autoimmune Disease Manifestations in the Oral Cavity. Surg Pathol Clin 10 (1):57-88. DOI:10.1016/j.path.2016.11.001 PMID: 28153136

[pmid23138121-3] Wang H, Qiao S, Zhang X, Liu C (2013). “A case of pyodermatitis-pyostomatitis vegetans”. Am J Med Sci. 345 (2): 168–71. doi:10.1097/MAJ.0b013e31826c5a82. PMID 23138121.

[pmid20689401-4] 4.0 ^4.1 Abellaneda C, Mascaró JM, Vázquez MG, Pablo IM, Iranzo P (2011). “All that glitters is not pemphigus: Pyodermatitis-pyostomatitis vegetans misdiagnosed as IgA pemphigus for 8 years”. Am J Dermatopathol. 33 (1): e1–6. doi:10.1097/DAD.0b013e3181d81ecb. PMID 20689401.

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