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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Streptomyces achromogenes

Introduction

Streptomyces achromogenes is a species of gram-positive bacterium that belongs in the genus Streptomyces. S. achromogenes can be grown at 26°C in a medium of yeast and malt extract with glucose .

S. achromogenes is the source of the restriction enzymes SacI and SacII,[1] as well as the antibiotic compound sarcidin.[2] A strain of the bacterium called S. achromogenes var. streptozoticus was the original source of the pancreatic cancer drug streptozotocin.[3]

References

  1. ↑ Zhuravleva L, Oreshkin E, Bezborodov A (1987). “Isolation and purification of restriction endonuclease SacI from Streptomyces achromogenes ATCC 12767”. Prikl Biokhim Mikrobiol. 23 (2): 208–15. PMID 3033630.
  2. ↑ Takeuchi T, Nitta K, Umezawa H (1953). “On an antibiotic, sarcidin, produced by Streptomyces n. sp. S. achromogenes”. J Antibiot (Tokyo). 6 (1): 31–2. PMID 13061372.
  3. ↑ Bolzán A, Bianchi M (2002). “Genotoxicity of streptozotocin”. Mutat Res. 512 (2–3): 121–34. PMID 12464347.

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