Subependymal giant cell astrocytoma MRI

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Ifeoma Odukwe, M.D. [2], Sujit Routray, M.D. [3]

Overview

On brain MRI, some of the findings that are suggestive of subependymal giant cell astrocytoma include T1 isointense and hypointense signal enhancement, T2 isointense and hyperintense signal enhancement, and enlargement of ventricles.

MRI

Brain MRI may be helpful in the diagnosis of subependymal giant cell astrocytoma. Findings on MRI suggestive of/diagnostic of subependymal giant cell astrocytoma include:^[1]^[2]

Well circumscribed mass
Perilesional edema
T1 isointense and hypointense signal enhancement
T2 isointense and hyperintense signal enhancement
Calcification
Cyst
Enlargement of ventricles
Homogenous postcontrast enhancement

Serial MRI’s every 1-3 years is recommended in asymptomatic patients younger than 25 as tumor growth is more common in these patients.^[1]

Axial T2 MRI showing a large lobulated intensely enhancing mass arising from the left foramen of Monro causing mild hydrocephalus. source:Case courtesy of Dr Amro Omar, <a href=”https://radiopaedia.org/”>Radiopaedia.org</a>. From the case <a href=”https://radiopaedia.org/cases/36589″>rID: 36589</a>

References

↑ ^1.0 ^1.1 Stein JR, Reidman DA (2016). “Imaging Manifestations of a Subependymal Giant Cell Astrocytoma in Tuberous Sclerosis”. Case Rep Radiol. 2016: 3750450. doi:10.1155/2016/3750450. PMC 4752974. PMID 26942030.
↑ Beaumont, Thomas L.; Godzik, Jakub; Dahiya, Sonika; Smyth, Matthew D. (2015). “Subependymal giant cell astrocytoma in the absence of tuberous sclerosis complex: case report”. Journal of Neurosurgery: Pediatrics. 16 (2): 134–137. doi:10.3171/2015.1.PEDS13146. ISSN 1933-0707.

Template:WikiDoc Sources

[pmid26942030-1] 1.0 ^1.1 Stein JR, Reidman DA (2016). “Imaging Manifestations of a Subependymal Giant Cell Astrocytoma in Tuberous Sclerosis”. Case Rep Radiol. 2016: 3750450. doi:10.1155/2016/3750450. PMC 4752974. PMID 26942030.

[BeaumontGodzik2015-2] Beaumont, Thomas L.; Godzik, Jakub; Dahiya, Sonika; Smyth, Matthew D. (2015). “Subependymal giant cell astrocytoma in the absence of tuberous sclerosis complex: case report”. Journal of Neurosurgery: Pediatrics. 16 (2): 134–137. doi:10.3171/2015.1.PEDS13146. ISSN 1933-0707.

[1]

[2]

Subependymal giant cell astrocytoma MRI

Overview

MRI

References

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