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Subependymal giant cell astrocytoma history and symptoms

Introduction

Overview

Overview

Patients with subependymal giant cell astrocytoma may have a positive history of tuberous sclerosis, seizures, and personality changes. Some common symptoms that may be present include headache, nausea, vomiting, and cognitive decline.

History and Symptoms

History and Symptoms

History

Patients with subependymal giant cell astrocytoma may have a positive history of:[1][2][3][4][5]

Common Symptoms

Majority of the symptoms experienced by patients with subependymal giant cell astrocytoma are due to obstruction of the foramen of monro. Common symptoms of subependymal giant cell astrocytoma include:[1][2][3][4][5]

Less Common Symptoms

Less common symptoms of subependymal giant cell astrocytoma include:[1][2][3][4][5]

  • Sleep disorder
  • Changes in speech
  • Weakness in limbs
  • Sensory loss
  • Fatigue
  • Decreased appetite
References

References

  1. ↑ 1.0 1.1 1.2 JΓ³ΕΊwiak S, Nabbout R, Curatolo P, participants of the TSC Consensus Meeting for SEGA and Epilepsy Management (2013). “Management of subependymal giant cell astrocytoma (SEGA) associated with tuberous sclerosis complex (TSC): Clinical recommendations”. Eur J Paediatr Neurol. 17 (4): 348–52. doi:10.1016/j.ejpn.2012.12.008. PMIDΒ 23391693.
  2. ↑ 2.0 2.1 2.2 Ouyang, Taohui; Zhang, Na; Benjamin, Thomas; Wang, Long; Jiao, Jiantong; Zhao, Yiqing; Chen, Jian (2014). “Subependymal giant cell astrocytoma: current concepts, management, and future directions”. Child’s Nervous System. 30 (4): 561–570. doi:10.1007/s00381-014-2383-x. ISSNΒ 0256-7040.
  3. ↑ 3.0 3.1 3.2 Symptoms of subependymal giant cell astrocytoma. University of Pittsburgh Medical Center 2015. http://www.upmc.com/services/neurosurgery/brain/conditions/brain-tumors/pages/subependymal-giant-cell-astrocytoma.aspx. Accessed on November 5, 2015
  4. ↑ 4.0 4.1 4.2 Koenig MK, Butler IJ, Northrup H (2008). “Regression of subependymal giant cell astrocytoma with rapamycin in tuberous sclerosis complex”. J Child Neurol. 23 (10): 1238–9. doi:10.1177/0883073808321764. PMCΒ 3072698. PMIDΒ 18952591.
  5. ↑ 5.0 5.1 5.2 Goh S, Butler W, Thiele EA (2004). “Subependymal giant cell tumors in tuberous sclerosis complex”. Neurology. 63 (8): 1457–61. doi:10.1212/01.wnl.0000142039.14522.1a. PMIDΒ 15505165.


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ifeoma Odukwe, M.D. [2], Sujit Routray, M.D. [3]