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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Syndecan-3

Introduction

Syndecan-3 is a protein that in humans is encoded by the SDC3 gene.[1][2][3]

References

References

  1. ↑ Carey DJ, Evans DM, Stahl RC, Asundi VK, Conner KJ, Garbes P, Cizmeci-Smith G (May 1992). “Molecular cloning and characterization of N-syndecan, a novel transmembrane heparan sulfate proteoglycan”. J Cell Biol. 117 (1): 191–201. doi:10.1083/jcb.117.1.191. PMC 2289399. PMID 1556152.
  2. ↑ Berndt C, Casaroli-Marano RP, Vilaro S, Reina M (Aug 2001). “Cloning and characterization of human syndecan-3”. J Cell Biochem. 82 (2): 246–59. doi:10.1002/jcb.1119. PMID 11527150.
  3. ↑ “Entrez Gene: SDC3 syndecan 3”.
Further reading

Further reading

  • Barillari G, Gendelman R, Gallo RC, Ensoli B (1993). “The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence”. Proc. Natl. Acad. Sci. U.S.A. 90 (17): 7941–5. doi:10.1073/pnas.90.17.7941. PMC 47263. PMID 7690138.
  • Raulo E, Chernousov MA, Carey DJ, et al. (1994). “Isolation of a neuronal cell surface receptor of heparin binding growth-associated molecule (HB-GAM). Identification as N-syndecan (syndecan-3)”. J. Biol. Chem. 269 (17): 12999–3004. PMID 8175719.
  • Chernousov MA, Carey DJ (1993). “N-syndecan (syndecan 3) from neonatal rat brain binds basic fibroblast growth factor”. J. Biol. Chem. 268 (22): 16810–4. PMID 8344959.
  • Albini A, Benelli R, Presta M, et al. (1996). “HIV-tat protein is a heparin-binding angiogenic growth factor”. Oncogene. 12 (2): 289–97. PMID 8570206.
  • Chernousov MA, Stahl RC, Carey DJ (1996). “Schwann cells secrete a novel collagen-like adhesive protein that binds N-syndecan”. J. Biol. Chem. 271 (23): 13844–53. doi:10.1074/jbc.271.23.13844. PMID 8662884.
  • Nakanishi T, Kadomatsu K, Okamoto T, et al. (1997). “Expression of syndecan-1 and -3 during embryogenesis of the central nervous system in relation to binding with midkine”. J. Biochem. 121 (2): 197–205. PMID 9089390.
  • Rusnati M, Coltrini D, Oreste P, et al. (1997). “Interaction of HIV-1 Tat protein with heparin. Role of the backbone structure, sulfation, and size”. J. Biol. Chem. 272 (17): 11313–20. doi:10.1074/jbc.272.17.11313. PMID 9111037.
  • Chang HC, Samaniego F, Nair BC, et al. (1997). “HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region”. AIDS. 11 (12): 1421–31. doi:10.1097/00002030-199712000-00006. PMID 9342064.
  • Asundi VK, Carey DJ (1997). “Phosphorylation of recombinant N-syndecan (syndecan 3) core protein”. Biochem. Biophys. Res. Commun. 240 (2): 502–6. doi:10.1006/bbrc.1997.7684. PMID 9388509.
  • Seki N, Ohira M, Nagase T, et al. (1998). “Characterization of cDNA clones in size-fractionated cDNA libraries from human brain”. DNA Res. 4 (5): 345–9. doi:10.1093/dnares/4.5.345. PMID 9455484.
  • Kinnunen T, Kaksonen M, Saarinen J, et al. (1998). “Cortactin-Src kinase signaling pathway is involved in N-syndecan-dependent neurite outgrowth”. J. Biol. Chem. 273 (17): 10702–8. doi:10.1074/jbc.273.17.10702. PMID 9553134.
  • Hsueh YP, Sheng M (1999). “Regulated expression and subcellular localization of syndecan heparan sulfate proteoglycans and the syndecan-binding protein CASK/LIN-2 during rat brain development”. J. Neurosci. 19 (17): 7415–25. PMID 10460248.
  • Rusnati M, Tulipano G, Spillmann D, et al. (1999). “Multiple interactions of HIV-I Tat protein with size-defined heparin oligosaccharides”. J. Biol. Chem. 274 (40): 28198–205. doi:10.1074/jbc.274.40.28198. PMID 10497173.
  • Tyagi M, Rusnati M, Presta M, Giacca M (2001). “Internalization of HIV-1 tat requires cell surface heparan sulfate proteoglycans”. J. Biol. Chem. 276 (5): 3254–61. doi:10.1074/jbc.M006701200. PMID 11024024.
  • Koroll M, Rathjen FG, Volkmer H (2001). “The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self-associating activity”. J. Biol. Chem. 276 (14): 10646–54. doi:10.1074/jbc.M010647200. PMID 11152476.
  • Hakansson S, Jacobs A, Caffrey M (2001). “Heparin binding by the HIV-1 tat protein transduction domain”. Protein Sci. 10 (10): 2138–9. doi:10.1110/ps.23401. PMC 2374215. PMID 11567105.
  • Erdman R, Stahl RC, Rothblum K, et al. (2002). “Schwann cell adhesion to a novel heparan sulfate binding site in the N-terminal domain of alpha 4 type V collagen is mediated by syndecan-3”. J. Biol. Chem. 277 (9): 7619–25. doi:10.1074/jbc.M111311200. PMID 11751872.
  • Alvarez K, Fadic R, Brandan E (2002). “Augmented synthesis and differential localization of heparan sulfate proteoglycans in Duchenne muscular dystrophy”. J. Cell. Biochem. 85 (4): 703–13. doi:10.1002/jcb.10184. PMID 11968010.