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Syphilis other diagnostic studies

Introduction

Overview

Overview

Other diagnostic studies which may help diagnose complications of syphilis are CSF examination, screening tests for other STIs such as HIV, chlamydia, gonorrhea, and biopsy.[1][2]

Other Diagnostic Studies

Other Diagnostic Studies

Other diagnostic studies which may help diagnose complications of syphilis are:[1][2]

CSF examination

  • May help to diagnose neurosyphilis
  • Includes CSF cell count or protein and a reactive CSF-VDRL or CSF FTA-ABS test
  • CSF-VDRL is highly specific but insensitive
  • CSF FTA-ABS test is less specific for neurosyphilis than the CSF-VDRL but is highly sensitive

Screening tests for other STIs

Biopsy

  • Biopsy may be considered if clinical findings do not correlate with negative serological tests and there is a strong index of suspicion for syphilis.
References

References

  1. ↑ 1.0 1.1 http://www.cdc.gov/std/tg2015/syphilis.htm accessed on September 28, 2016
  2. ↑ 2.0 2.1 Luger AF, Schmidt BL, Kaulich M (2000). “Significance of laboratory findings for the diagnosis of neurosyphilis”. Int J STD AIDS. 11 (4): 224–34. PMID 10772085.


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2]