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Systemic lupus erythematosus other diagnostic studies

Introduction

Overview

Overview

Other diagnostic tests that can be used for diagnosis of complications include a barium swallow for stricture diagnosis, biopsies of the kidneys and the endometrium for further evaluation of the degree of involvement, paracentesis to evaluate effusions, and arthrocentesis to differentiate different causes of arthritis.

Other Diagnostic Studies

Other Diagnostic Studies

Bronchoscopy

Fiberoptic bronchoscopy with bronchoalveolar lavage (BAL) and transbronchial lung biopsies:[1][2]

  • To substantiate the diagnosis of alveolar hemorrhage

Barium swallow or esophagography

Biopsy

  • Renal biopsies:[4][5]
    • Determining the degree of renal involvement
    • Delineating treatment decisions and prognosis in certain clinical scenarios
    • Assess activity and damage (i.e., chronicity)
    • Helping with classification

Paracentesis

Arthrocentesis

  • In the presence of joint effusion to differentiate between different causes of arthritis[10]
References

References

  1. ↑ Shen M, Wang Y, Xu WB, Zeng XJ, Zhang FC (2005). “[Pleuropulmonary manifestations of systemic lupus erythematosus]”. Zhonghua Yi Xue Za Zhi (in Chinese). 85 (48): 3392–5. PMIDΒ 16409858.
  2. ↑ Susanto I, Peters JI (1997). “Acute lupus pneumonitis with normal chest radiograph”. Chest. 111 (6): 1781–3. PMIDΒ 9187214.
  3. ↑ 3.0 3.1 JimΓ©nez-Alonso J, Estev D, Vera C, Sabio JM (2003). “Dysphagia in patients with systemic lupus erythematosus”. Lupus. 12 (6): 493. PMIDΒ 12873055.
  4. ↑ Giannico G, Fogo AB (2013). “Lupus nephritis: is the kidney biopsy currently necessary in the management of lupus nephritis?”. Clin J Am Soc Nephrol. 8 (1): 138–45. doi:10.2215/CJN.03400412. PMIDΒ 22977215.
  5. ↑ Singh A, Ghosh R, Kaur P, Golay V, Pandey R, Roychowdhury A (2014). “Protocol renal biopsy in patients with lupus nephritis: a single center experience”. Saudi J Kidney Dis Transpl. 25 (4): 801–7. PMIDΒ 24969191.
  6. ↑ Salomone E, Tamburino C, Bruno G, Di Paola R, Silvestri F (1989). “The role of endomyocardial biopsy in the diagnosis of cardiac involvement in systemic lupus erythematosus”. Heart Vessels. 5 a (1): 52–3. PMIDΒ 2684953.
  7. ↑ Prasad S, Abujam B, Lawrence A, Aggarwal A (2012). “Massive ascites as a presenting feature of lupus”. Int J Rheum Dis. 15 (1): e15–6. doi:10.1111/j.1756-185X.2011.01659.x. PMIDΒ 22324961.
  8. ↑ Palavutitotai N, Buppajarntham T, Katchamart W (2014). “Etiologies and outcomes of pleural effusions in patients with systemic lupus erythematosus”. J Clin Rheumatol. 20 (8): 418–21. doi:10.1097/RHU.0000000000000179. PMIDΒ 25417677.
  9. ↑ Kruzliak P, Novak M, Piler P, Kovacova G (2013). “Pericardial involvement in systemic lupus erythematosus: current diagnosis and therapy”. Acta Cardiol. 68 (6): 629–33. doi:10.2143/AC.68.6.8000011. PMIDΒ 24579442.
  10. ↑ Goldenberg DL, Cohen AS (1978). “Synovial membrane histopathology in the differential diagnosis of rheumatoid arthritis, gout, pseudogout, systemic lupus erythematosus, infectious arthritis and degenerative joint disease”. Medicine (Baltimore). 57 (3): 239–52. PMIDΒ 642792.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mahshid Mir, M.D. [2]