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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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T-cell prolymphocytic leukemia classification

Introduction

Overview

Overview

T-cell prolymphocytic leukemia is classified into three variants based on its morphology.

Classification

Classification

T-cell prolymphocytic leukemia classification is based on its morphology. [1][2][3][4]

    Morphological Variant Percentage of total number
    Typical T-cell prolymphocytic leukemia 75 percent
    Small cell variant 20 percent
    Cerebriform (Sézary cell-like) variant 5 percent
    References

    References

    1. ↑ Graham RL, Cooper B, Krause JR (2013). “T-cell prolymphocytic leukemia”. Proc (Bayl Univ Med Cent). 26 (1): 19–21. PMC 3523759. PMID 23382603.
    2. ↑ Swerdlow SH, Campo E, Pileri SA, Harris NL, Stein H, Siebert R, Advani R, Ghielmini M, Salles GA, Zelenetz AD, Jaffe ES (May 2016). “The 2016 revision of the World Health Organization classification of lymphoid neoplasms”. Blood. 127 (20): 2375–90. doi:10.1182/blood-2016-01-643569. PMC 4874220. PMID 26980727.
    3. ↑ Matutes E, Brito-Babapulle V, Swansbury J, Ellis J, Morilla R, Dearden C, Sempere A, Catovsky D (December 1991). “Clinical and laboratory features of 78 cases of T-prolymphocytic leukemia”. Blood. 78 (12): 3269–74. PMID 1742486.
    4. ↑ Foucar K (April 2007). “Mature T-cell leukemias including T-prolymphocytic leukemia, adult T-cell leukemia/lymphoma, and Sézary syndrome”. Am. J. Clin. Pathol. 127 (4): 496–510. doi:10.1309/KWJYBCCGTB90B6AE. PMID 17369126.

    Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Qurrat-ul-ain Abid, M.D.[2], Maria Fernanda Villarreal, M.D. [3]