T-cell prolymphocytic leukemia classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Qurrat-ul-ain Abid, M.D.[2], Maria Fernanda Villarreal, M.D. [3]

Overview

T-cell prolymphocytic leukemia is classified into three variants based on its morphology.

Classification

Morphological Variant	Percentage of total number
Typical T-cell prolymphocytic leukemia	75 percent
Small cell variant	20 percent
Cerebriform (Sézary cell-like) variant	5 percent

References

↑ Graham RL, Cooper B, Krause JR (2013). “T-cell prolymphocytic leukemia”. Proc (Bayl Univ Med Cent). 26 (1): 19–21. PMC 3523759. PMID 23382603.
↑ Swerdlow SH, Campo E, Pileri SA, Harris NL, Stein H, Siebert R, Advani R, Ghielmini M, Salles GA, Zelenetz AD, Jaffe ES (May 2016). “The 2016 revision of the World Health Organization classification of lymphoid neoplasms”. Blood. 127 (20): 2375–90. doi:10.1182/blood-2016-01-643569. PMC 4874220. PMID 26980727.
↑ Matutes E, Brito-Babapulle V, Swansbury J, Ellis J, Morilla R, Dearden C, Sempere A, Catovsky D (December 1991). “Clinical and laboratory features of 78 cases of T-prolymphocytic leukemia”. Blood. 78 (12): 3269–74. PMID 1742486.
↑ Foucar K (April 2007). “Mature T-cell leukemias including T-prolymphocytic leukemia, adult T-cell leukemia/lymphoma, and Sézary syndrome”. Am. J. Clin. Pathol. 127 (4): 496–510. doi:10.1309/KWJYBCCGTB90B6AE. PMID 17369126.

Overview