T-cell prolymphocytic leukemia epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Qurrat-ul-ain Abid, M.D.[2], Maria Fernanda Villarreal, M.D. [3]

Overview

T-cell prolymphocytic leukemia is a rare condition. Its incidence increases with age, and with ataxia telangiectasia. The median age at diagnosis is 30 years.

Epidemiology and Demographics

T-cell prolymphocytic leukemia is very rare, and it represents 2% of all small lymphocytic leukemias in adults.
The incidence of T-cell prolymphocytic leukemia increases with age; the median age at diagnosis is 65 years.^[1]
Patients with ataxia telangiectasia and T-cell prolymphocytic leukemia are young adults; the median age at diagnosis is 30 years.
Males are slightly more affected with T-cell prolymphocytic leukemia than females.
There is no racial predilection for T-cell prolymphocytic leukemia.
T-PLL is a rare leukemia, primarily affecting adults over the age of 30. It represents 2% of all small lymphocytic leukemias in adults.^[2]

References

↑ Graham RL, Cooper B, Krause JR (2013). “T-cell prolymphocytic leukemia”. Proc (Bayl Univ Med Cent). 26 (1): 19–21. PMC 3523759. PMID 23382603.
↑ Matutes E, Brito-Babapulle V, Swansbury J; et al. (1991). “Clinical and laboratory features of 78 cases of T-prolymphocytic leukemia”. Blood. 78 (12): 3269–74. PMID 1742486.

Overview